Clinical Trials: Cardiology
The Taft Center for Clinical Research is currently conducting clinical trials in multiple areas of medicine, including Cardiology.
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Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation – APOLLO Trial
Study Type/Phase: Pivotal, Multi-center, Global, pre-market trial
Status: Recruiting
This research trial is a Pivotal Study of mitral valve replacement using a new, investigational device called the Medtronic Intrepid™ TMVR system. The purpose of this clinical study is to determine if replacing the mitral valve without...
AVENTUS: Assessing the Safety and Efficacy of the treatment for Acute Pulmonary Embolism using the Inquis Medical Aventus Thrombectomy System
Study Type/Phase: Prospective, Single Group Assignment, Safety & Efficacy
Status: Recruiting
Pulmonary embolism (PE) is a major cause of morbidity and mortality that occurs when particles/thrombi that have formed within the blood stream are dislodged and travel to the lung causing a reduced ability to breathe...
Watchman FLX versus NOAC for the Embolic Protection in the Management of Patients with non-Valvular Atrial Fibrillation (Champion-AF)
Study Type/Phase: Prospective, Randomized, Multi-center Global Investigation
Status: Not Recruiting
This research study addresses a common sustained heart rhythm disorder known as non-valvular atrial fibrillation (AF). Atrial fibrillation affects your heart’s ability to pump blood normally, causing blood...
Clinical Trial to Evaluate Cardiovascular Outcomes in Patients Treated with the Tricuspid Valve Repair System Pivotal (TRILUMINATE Pivotal)
Study Type/Phase: Pivotal, Randomized, Single Arm
Status: Recruiting
The tricuspid heart valve separates the right lower heart chamber (the right ventricle) from the right upper heart chamber (right atrium)...
Transcatheter Aortic Valve Replacement (TAVR) in Patients with the Medtronic Transcatheter Aortic Valve Replacement System in Patients at Low Risk for Surgical Aortic Valve Replacement (SAVR) Continued Access Trial
Study Type/Phase: Prospective, non-randomized, continued access trial
Status: Not Recruiting
Open heart surgery, or surgical aortic valve replacement (SAVR), is the standard treatment for patients with severe aortic stenosis who are at low predicted risk for experiencing major complications...
Amplatzer Amulet Left Atrial Appendage Occluder Randomized Controlled Trial
Phase: Pivotal
Status: Not Recruiting
This research study examines the most common sustained heart rhythm disorder, known as non-valvular atrial fibrillation (AF) and its effects of increased risk of stroke and systemic embolism or blood clots blocking an artery. ...
Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI)
Phase: II/III
Status: Not Recruiting
The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical ...
Transcatheter Aortic Valve Replacement with the Medtronic Transcatheter Aortic Valve Replacement System in Patients at Low Risk for Surgical Aortic Valve Replacement
Phase: Pivotal
Status: Not Recruiting
This research study examines the disease of the aortic valve known as aortic stenosis. ...
